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Autoimmune Diseases: Types, Symptoms & Treatments
Autoimmune diseases are chronic conditions. This means if you have an autoimmune disease, you’ll probably have to manage it and the symptoms it causes for the rest of your life. Types of autoimmune diseases There are more than 100 different autoimmune diseases.

Autoimmune Diseases: Symptoms, Causes & Treatments - Healthline
Learn about autoimmune diseases, including common symptoms, causes, and treatments. Discover types like rheumatoid arthritis, lupus, and more.

List of autoimmune diseases, with symptoms and treatments
There are more than 100 autoimmune diseases that scientists know about today. This article provides a list of autoimmune diseases and some of their symptoms.

Autoimmune disease - Wikipedia
An autoimmune disease is a condition causing disease that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms. [1] It is estimated that there are more than 80 recognized autoimmune diseases, with recent scientific evidence suggesting the existence of potentially more ...

List of autoimmune diseases - Wikipedia
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed with the condition. Each disorder is also ...

Autoimmune Diseases: Causes, Symptoms, and Treatments - WebMD
Learn about the causes, symptoms, and treatments of autoimmune diseases in this informative guide. Take charge of your health and find the support you need.

Autoimmune Disease List: Symptoms, Causes & Treatments
Explore our complete list of autoimmune diseases, with in-depth information on symptoms, causes, risk factors, and treatment options.

Autoimmune Disease: Types, Symptoms, and More - Verywell Health
Autoimmune diseases occur when the immune system attacks the body’s own cells. Learn about the types and causes. Reviewed by a board-certified internist.

Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets
Keywords: autoimmune diseases, immune tolerance, pathogenesis, therapeutic strategies This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.

A-Z Autoimmune Disease List - Global Autoimmune Institute
A-Z Autoimmune Disease List This A-Z list and basic information about each recognized or suspected autoimmune disease were compiled and written by our dedicated research team at the Global Autoimmune Institute. The list provides a starting point in learning about confirmed and suspected autoimmune diseases, with links to other sources that we believe to be accurate and informative. This ...

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*Filter: "Autoimmune-disease"

Females with autoimmune diseases ‘less likely to be believed’ than males and face longer diagnostic delays  University of Cambridge
Color Changes in Fingers May Signal Autoimmune Disease, Doctor Says  Seoul Economic Daily
What doctors want patients to know about rheumatoid arthritis  American Medical Association | AMA
How did Bryan Johnson end up with an autoimmune disease?  Northeastern Global News
Christina Applegate says her doctor told her she was misdiagnosed with MS  CityNews Vancouver
Scientists explore new frontier in autoimmune disease treatment by resetting 'rogue' cells  PBS
The daring doctor behind a world-first treatment for autoimmune disease  Nature
‘All in your head’: when doctors misdiagnose autoimmune disease as psychosomatic  The Conversation
Q&A: What makes autoimmune diseases so difficult to manage?  ASU News
A breakthrough cancer immunotherapy is now taking aim at autoimmune disease  Science | AAAS
Finding Suggests Treatment Approach for Autoimmune Diseases  NYU Langone Health
Experts Discuss the Complex Path to an Autoimmune Diagnosis  Global Autoimmune Institute
Autoimmune disease and COVID-19: a complicated relationship  UCHealth
Who Am I Now?: Living with an Autoimmune Disease  HSS | Hospital for Special Surgery
New cellular therapy approach at MUSC targets lupus and other autoimmune diseases  The Medical University of South Carolina

Common Rheumatological Symptoms

Joint Pain (Arthralgia) — Persistent discomfort or soreness in one or more joints caused by inflammation, wear and tear, or underlying autoimmune responses.
Morning Stiffness — Reduced joint mobility and tightness upon waking, often lasting over 30 to 60 minutes in inflammatory conditions like rheumatoid arthritis.
Joint Swelling and Edema — Visible enlargement of affected joints resulting from fluid accumulation in the synovial membrane and inflamed surrounding tissue.
Localized Warmth and Redness — Elevated temperature and erythema skin discoloration surrounding inflamed joints due to increased blood flow from localized inflammation.
Systemic Fatigue — Overwhelming exhaustion and lack of energy caused by ongoing chronic inflammatory cytokine activity throughout the body.
Raynaud's Phenomenon — Temporary color changes in fingers or toes turning white, blue, and red in response to cold or stress due to vascular spasms.
Malar or Butterfly Rash — Red or purplish facial rash spanning across the bridge of the nose and cheeks, classically associated with systemic lupus erythematosus.

Milestones in Rheumatology History

c. 400 BC: Hippocratic Corpus Coining — Hippocrates uses the term "rheuma" to describe body humors flowing into joints, establishing the early classical concept of joint inflammation.
1592: Formal Definition of Rheumatism — French physician Guillaume de Baillou introduces the modern term "rheumatism" to distinguish systemic acute arthritis from localized gout.
1800: Clinical Description of Rheumatoid Arthritis — Augustin Jacob Landré-Beauvais publishes the first detailed clinical description separating rheumatoid arthritis from gout, calling it "asthenic gout."
1859: Naming of Rheumatoid Arthritis — Sir Alfred Baring Garrod formally coins the term "rheumatoid arthritis" to clearly differentiate the inflammatory autoimmune condition from osteoarthritis and gout.
1940: Discovery of the Rheumatoid Factor — Erik Waaler discovers autoantibodies in the blood of patients with rheumatoid arthritis, laying the groundwork for serological autoimmune diagnostics.
1948: Introduction of Corticosteroid Therapy — Philip Hench and Edward Kendall demonstrate the dramatic anti-inflammatory effects of Compound E (cortisone) in treating rheumatoid arthritis, earning the Nobel Prize.
1998: Emergence of Biologic DMARDs — The FDA approves the first TNF-alpha inhibitors, ushering in the modern era of targeted biologic therapies for autoimmune rheumatic diseases.

Current Trends in Rheumatology Research

Chimeric Antigen Receptor (CAR) T-Cell Reset Therapy — Investigating engineered cellular therapies to achieve drug-free, durable clinical remissions by completely depleting pathogenic autoantibodies in severe refractory lupus and systemic sclerosis.
Selective TYK2 and Oral JAK Pathway Inhibition — Developing highly targeted, small-molecule oral inhibitors like deucravacitinib that disrupt specific cytokine signaling pathways while minimizing broader off-target side effects.
Targeted Pathogenic T-Cell and B-Cell Depletion — Evaluating novel biologics, such as rosnilimab and ianalumab, designed to selectively deplete overactive immune cell subpopulations involved in rheumatoid arthritis and Sjögren's disease.
Biomarker-Driven Precision Medicine — Utilizing pharmacogenomics and molecular biomarkers to predict individualized therapeutic responses and match systemic autoimmune conditions to specific biological mechanisms.
Subclinical Interception and Disease Prevention — Identifying seropositive individuals early using high-risk autoantibody profiles to initiate preventive targeted therapies before irreversible joint damage occurs.
Artificial Intelligence and Predictive Disease Modeling — Deploying machine learning algorithms across electronic health records and imaging modalities to forecast inflammatory flares and refine diagnostic accuracy.